Skin Bio-Remodelling Treatment | Advanced Polynucleotide Treatment

What is Skin Bio-remodelling treatment?

Skin bio-remodelling treatments, also known as bio-stimulators or skin boosters, work deep within the skin layers to add volume, restore hydration, improve texture and laxity and increase firmness. These innovative treatments offer a comprehensive approach to facial rejuvenation without surgery.

Newest by Mastelli offers the latest in skin bio-remodelling technology, uniquely formulated with polynucleotides (PN-HPT) and non-cross linked hyaluronic acid. This powerful combination delivers the dual benefits of both bio-stimulators and hyaluronic acid dermal fillers for powerful skin rejuvenation results. When used together, polynucleotides and non-cross linked hyaluronic acid provide a comprehensive approach to addressing signs of aging:

  • Hyaluronic acid can replenish lost volume and enhance overall facial symmetry
  • Polynucleotides activate the body’s natural repair mechanisms at the cellular level
  • Together, they reduce existing signs of aging while preventing future damage
  • The result is improved skin radiance, luminosity, and texture

When used together, polynucleotides and non-cross linked hyaluronic acid provide a comprehensive approach to addressing signs of aging.

Mr Olivier Amar

Your consultation

Whether meeting in person or remotely, your consultation with Mr Olivier Amar provides a comprehensive discussion of your hoped for goals and treatment options. To get the most out of your consultation, we recommend reviewing information about your area of interest beforehand.

During your consultation, Mr Olivier Amar will listen to your desired outcomes and goals, conduct a thorough assessment, present appropriate treatment options and explain procedures in detail. This will include a step-by-step treatment process, required preparation, recovery timeline and potential risks and complications.

A consultation ensures you receive comprehensive information about all options, and understand both benefits and limitations of proposed procedures. You will have the opportunity to ask as many questions as you wish before you decide the next steps together, including the option to take no action.

Advanced Facial Rejuvenation

Mr Olivier Amar specialises in facial rejuvenation treatments. As every face is unique and we all age in different ways, he will conduct a comprehensive facial assessment, carefully developing a tailored approach to help patients achieve subtle, natural rejuvenation.

Risks associated with treatment

Every non-surgical treatment, while performed with the utmost care and expertise, carries inherent risks. Mr Olivier Amar ensures all patients are fully informed about potential complications before proceeding with any treatment.

General treatment side effects are generally mild and temporary, including redness, swelling, bruising and minor discomfort. During your consultation, Mr Olivier Amar will provide detailed information about procedure specific risks, explain preventive measures and safety protocols, answer all questions about potential complications and provide you with all the information needed to make an informed decision.

Preparing for Your Treatment

Aim to arrive to your appointment with your skin as best prepared for your Skin Bio-remodelling treatment as it can be.

Pre-treatment guidelines would ideally include:

• Avoid ibuprofen and aspirin 48 hours prior to treatment
• Avoid alcohol 2-3 days before treatment
• Get adequate rest the night before
• Eat a light meal and stay hydrated
• Clean skin thoroughly before treatment

Patients with a history of herpes simplex virus should be aware that, like many facial procedures, this treatment may trigger the virus and lead to cold sores. If you have experienced cold sores in the past, please inform us so we can prescribe preventative antiviral medication before your treatment.

Recovery Guide

Immediately after treatment you may experience bruising, mild redness, swelling, tenderness and itching at the site of the treated areas. Most patients find that any side effects subside within 2-3 days.

No downtime is required and you can resume normal activities immediately, avoiding strenuous exercise for 24 hours to prevent increasing blood flow to the face. As with all facial treatments, you should avoid direct sun exposure until any bruising subsides, continue using SPF 50+ protection and follow our recommended skincare routine.

Maintaining your results

Some patients will notice immediate results, while others may see gradual results that appear over time. Results depend on the age of the skin and concern being treated.

Most patients experience the best results within three months of completing the course of treatments, with a 4th treatment at four months to boost ongoing improvement. After this, results usually last for around six months and then most patients go on to repeat the treatment yearly. It is also recommended that you commit to wearing sun protection daily and follow an at home skincare regimen.

What are the benefits of Skin Bio-remodelling treatment?

You might consider skin bio-remodelling treatment to:

  • Improve deeper lines and wrinkles on the face, neck, hands and décolletage
  • Define and sculpt the jaw and enhance the chin for a balanced, youthful and structured jawline
  • Enhance skin hydration, circulation and overall skin quality
  • Boost collagen and elastin production for comprehensive rejuvenation of the face and neck
  • Fill temple hollows to subtly lift the outer brow
  • Restore smooth, youthful contours to the face
  • Improve the appearance of bumps or irregularities on the nose (non-surgical rhinoplasty)

What are Polynucleotides?

Polynucleotide injections have gained popularity within the range of skin regenerative treatments supporting overall skin longevity and wellness. Polynucleotides are an injectable bio-stimulator treatment that harnesses natural polymerised polynucleotide based injectable gel technology to effectively restore skin firmness, tone and elasticity.

Unlike traditional fillers, this innovative treatment works at the cellular level to promote natural skin regeneration. Polynucleotides deliver three powerful skin benefits:

  • Deep moisturisation for lasting hydration
  • Reduction of free radical damage to protect skin cells
  • Enhanced collagen production for improved skin structure

The treatment involves a series of polynucleotide injections that stimulate skin regeneration from within. This comprehensive approach restores skin tone, enhances hydration and visibly reduces wrinkles, resulting in radiant, luminous skin with improved texture and diminished signs of ageing.

Frequently Asked Questions

WHAT AREAS CAN BE TREATED WITH skin bio-remodelling treatment?

Skin Bio-remodelling treatment can treat the following areas:

  • Under eyes and peri-orbital area
  • Forehead and between the brows
  • Cheeks
  • Nasolabial folds
  • Smokers lines and lines around the mouth
  • Jawline
  • Neck
  • Decolletage
  • Hands

How many sessions will I need?

The recommended treatment is three sessions, two to three weeks apart with a fourth session at four months to boost ongoing improvement. Most patients go on to repeat the treatment yearly.

What is the difference between cross-linked and non-cross-linked hyaluronic acid?

Hyaluronic acid is a naturally found chemical in the skin, joints, and other connective tissues of the body. It is a gel like substance that plays a role in maintaining the hydration of the skin and tissues. It moisturises skin, rejuvenates skin cells, and reduces the appearance of wrinkles and fine lines. 

Hyaluronic acid, in its natural form, is non-cross linked and breaks down at a faster rate. Therefore it is chemically modified to create cross linked HA which is a thicker gel. While cross linked hyaluronic is far more stable and durable compared to its natural state. The process of cross linking makes the product thicker and more difficult for the body’s enzymes to break down and disintegrate. 

IS THE TREATMENT PAINFUL?

Most patients experience minimal discomfort. The needle used is very fine and the treatment involves several small injections.

How are Polynucleotides different from dermal fillers?

Unlike dermal fillers that add volume, polynucleotides operate at the cellular level to trigger your skin’s natural renewal processes. Making polynucleotides ideal for patients looking for natural looking skin rejuvenation.

Polynucleotides

  • Primary function: Skin regeneration and repair
  • How it works: Stimulates fibroblasts to boost collagen and elastin production
  • Results: Improved texture, elasticity and natural looking rejuvenation

Dermal Fillers

  • Primary function: Volume enhancement
  • How it works: Adds structural support to specific areas
  • Results: Improved volume and definition

HOW LONG DOES TREATMENT TAKE?

The treatment can take between 20 and 30 minutes, depending on the area being treated.

What are the benefits of polynucleotides and non-cross linked hyaluronic acid combined?

The combination of dermal fillers and polynucleotides offers a comprehensive approach to facial and body rejuvenation. While dermal fillers provide immediate volume and contouring, polynucleotides work over time to improve the skin’s quality, making the results more natural and longer lasting.

  • Enhanced results: polynucleotides improve skin texture and elasticity, creating a smoother canvas for dermal fillers. This combination ensures that the filler results look more natural and refined.
  • Longer lasting effects: polynucleotides extend the longevity of dermal fillers by promoting healthier skin. Healthier skin holds fillers better, meaning the results can last longer than fillers alone.
  • Holistic rejuvenation: by addressing both the volume loss and skin quality, this combination treatment offers a more holistic approach to anti-ageing. Patients can enjoy a youthful appearance with natural looking results.

What type of Polynucleotides does Mr Amar offer?

Mr Olivier Amar uses premium brands like Plinest and Newest from Mastelli that feature polymerised polynucleotide based injectable gels that stimulate fibroblasts. The Mastelli range contain highly purified DNA fragments extracted from trout fish, which offers bio revitalisation treatments tailored to different concerns, goals and treatment areas. The key benefits include:

Plinest by Mastelli: Designed to revitalise skin and improve overall skin quality, addressing hydration, tone and texture, dull skin and fine lines

Plinest Eyes by Mastelli: Formulated to improve the skin around the eyes area, addressing dark circles, fine lines, crepey skin and puffiness

Newest by Mastelli: Uniquely formulated with polynucleotides (PN-HPT) and non-cross linked hyaluronic acid. This powerful combination delivers the dual benefits of both bio-stimulators and hyaluronic acid dermal fillers for powerful skin rejuvenation results

How does Polynucleotides treatment differ to Profhilo?

Polynucleotides treatment and Profhilo both offer distinct benefits for skin rejuvenation. Profhilo, containing high concentrations of hyaluronic acid, delivers immediate hydration benefits. Patients typically notice an instant luminous glow and improved skin texture shortly after treatment. Polynucleotides work at a deeper cellular level, stimulating fibroblast activity and promoting natural collagen production, with longer lasting skin quality improvements through skin repair and regeneration.

Meet Olivier Amar – Leading Plastic Surgeon in Chelsea, London

Mr Olivier Amar is a renowned London based consultant plastic, reconstructive and aesthetic surgeon specialising in face, breast and body surgery, advanced non-surgical facial rejuvenation, hair loss treatments and regenerative medicine. With over 15 years of experience, Mr Olivier Amar has earned a reputation among both patients and peers alike for transforming cosmetic surgery into an art form.

“Cosmetic surgery is a demanding profession and patient expectations are high. But I am a doctor first and a surgeon second. My only concern is the patient in front of me, fulfilling their needs and managing their expectations. My work is intense; it means everything to me and is my lifelong passion.”

Mr Amar’s commitment to precision and refinement extends through every aspect of patient care, from initial consultation to post-operative support. All treatments take place at his private practice in Chelsea, London. Working alongside Mr Amar is a highly skilled team of dedicated nurses, experienced anaesthetists from leading NHS and private hospitals, and specialised management staff. This collaborative approach ensures comprehensive, world class care for all patients.